Anmol Chemicals is the pioneer manufacturers of Methylene Blue, Pharmaceutical Excipients Fragrance & Flavor chemicals in India. We offer Halal and Kosher Methylene Blue made in an ISO9001:2008, ISO22000:2005 (FSSC22000) and cGMP certified facility. Our group has several manufacturing facilities spread across the world, supported by toll manufacturers and representatives in UAE, Europe, Africa, USA, China and has several associated manufacturing facilities spread across India. All the Information on Physics, Chemistry, Applications, Uses and Technology on Manufacture of Methylene Blue is in these pages. The units have one or more of the certifications like FDA GMP, ISO 9001, ISO 22000, HACCP, REACH, Kosher & Halal
Methylthioninium Chloride, Methylene Blue SDS GHS, MSDS Sheet
Methylene Blue SDS GHS, MSDS Sheet, Material Safety Data Sheet
1. Product Identification
Synonyms: Basic Blue 9,trihydrate; Methelyne blue trihydrate; 3,7-Bis(dimethylamino)phenazathionium chloride trihydrate; Methylthioninium Chloride
CAS No.: 61-73-4 (Anhydrous); 7220-79-3 (Trihydrate)
EINECS EC Number: 200-515-2
Molecular Weight: 373.91
Chemical Formula: C16H18ClN3S-3H2O
Recommended usage: Industrial Manufacturing.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, oral Category 4
Skin corrosion/irritation Category 2
Serious eye damage/eye irritation Category 2A
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3
Labeling according Regulation (EC) No 1272/2008
GHS Label Elements
Signal Words: Warning
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash skin thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P270: Do not eat, drink or smoke when using this product.
P273: Avoid release to the environment.
P330: Rinse mouth.
P362: Take off contaminated clothing and wash before reuse.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P332+313: If skin irritation occurs: Get medical advice/attention.
P302+ P352 - IF ON SKIN: Wash with plenty of soap and water.
P305+ P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+313: If skin irritation occurs: Get medical advice/attention.
P337+P313 If eye irritation persists: Get medical advice/ attention.
P501: Dispose of contents/container to authorized agents only.
Labeling in accordance with Directive 67/548/EEC:
Xi Irritant; R22: Harmful if swallowed. R36/37/38: Irritating to eyes, respiratory system & skin.
For the full text of the H-statements & R-phrases mentioned in this Section, see Section 16.
3. Composition/Information on Ingredients
Ingredient: Methylene Blue
CAS No.: 61-73-4
4. First Aid Measures
Inhalation: Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm and quiet; get medical attention.
Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person.
Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get medical attention.
5. Fire Fighting Measures
Fire: Methylene blue is considered to be a fire hazard.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture: Carbon oxides, Nitrogen oxides (NOx), Sulphur oxides, Hydrogen chloride gas
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece.
6. Accidental Release Measures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Avoid breathing dust. Do not let product enter drains.
Ventilate area of leak or spill. Wear appropriate personal protective equipment. Pick up spills and place in a suitable container for reclamation or disposal, using a method that does not generate dust.
7. Handling and Storage
Keep Methylene Blue in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Avoid dust formation and control ignition sources. Isolate from incompatible substances. Containers of Methylene Blue may be hazardous when empty.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established.
Ventilation System: In general, dilution ventilation is a satisfactory health hazard control for this substance. However, if conditions of use create discomfort to the worker, a local exhaust system should be considered.
Personal Respirators (NIOSH Approved): Not expected to require personal respirator usage. For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerin, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance: Methylene Blue is dark green crystals with bronze luster or crystalline powder.
Solubility: Soluble in water.
Specific Gravity: No information found.
pH: No information found.
% Volatile by volume @ 21C (70F): 0
Boiling Point: Decomposes.
Melting Point: 190 °C
10. Stability and Reactivity
Stability: Methylene Blue is stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: May produce oxides of nitrogen, sulfur and carbon when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents, alkali, dichromates, alkali iodides, reducing agents.
Conditions to Avoid: Heat, flame, ignition sources, dusting and incompatibles.
11. Toxicological Information
Methylene Blue: 1180 mg/kg LD50 oral rat. Investigated as a mutagen, reproductive effector.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
12. Ecological Information
Environmental Fate: When released into the soil, this material is not expected to evaporate significantly. When released into water, this material is not expected to evaporate significantly. This material has an estimated bioconcentration factor (BCF) of less than 100. This material is not expected to significantly bioaccumulate. When released into the air, this material is expected to be readily degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material may be removed from the atmosphere to a moderate extent by wet deposition. When released into the air, this material may be removed from the atmosphere to a moderate extent by dry deposition.
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. Dispose of container and unused Methylene Blue in accordance with legal requirements.
14. Transport Information
DOT: Not regulated
TDG: Not regulated
IATA: Not regulated
IMDG/IMO: Not regulated
ADR/RID: Not regulated
15. Regulatory Information
TSCA 12(b): Not applicable
SARA 313: Not applicable
SARA 311/312 Hazardous Categorization: Acute Health Hazard, Chronic Health Hazard.
Clean Water Act: Not applicable
Clean Air Act: Not applicable
OSHA: Not applicable
CERCLA: Not applicable
California Proposition 65: This product does not contain any Proposition 65 chemicals
HMIS (Perceived): Health Hazard: 2, Fire Hazard: 1, Reactivity: 0, Personal Protection: E
NFPA (Perceived): Health: 2, Flammability: 1, Reactivity: 0
Canada WHMIS: D1B Toxic materials, D2B Toxic materials
16. Other Information
EINECS EC Number: 200-515-2
H302 = Harmful if swallowed.
H315 = Causes skin irritation.
H319 = Causes serious eye irritation.
H335 = May cause respiratory irritation.
Symbols: Xi Irritant
R22 = Harmful if swallowed. R36/37/38: Irritating to eyes, respiratory system and skin.
S26 = In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 = Wear suitable protective clothing.
Our company provides this Methylene Blue MSDS information sheet contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This Methylene Blue MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
Methylene Blue USP Manufacturers:
S-8, SARIFA MANSION, 2ND FLANK ROAD, CHINCHBUNDER, MUMBAI 400009, INDIA
TEL: (OFFICE) 91-22-23770100, 23726950, 23774610, 23723564 - FAX: 91-22-23728264
Methylene Blue Manufacturers
Exports to USA, Canada, UAE, Dubai, South Africa, Tanzania, Kenya, Nigeria, Egypt, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Europe Netherlands, Italy, Spain, Germany, Portugal, France, Malaysia, Indonesia, Thailand, Korea, Japan,etc.
Copyright and Usual Disclaimer is Applicable. 10 February, 2016
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